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Associate Director, Medicinal Chemistry

Location: South San Francisco, California Salary: competitive
Sector: R&D Type: Permanent

Requirements:

Ph.D. in Chemistry, Medicinal Chemistry, or related field

3 years minimum experience, 5+ years ideal

Experience working with CROs

Strong theoretical foundation in chemistry

Worked from late-stage discovery to early development

Experience working with non-classical drug targets (protein-protein interaction)

Troubleshooting experience

Understand possibility of molecules based on composition

Manage outsourced chemistry

Responsibility:

Manage outsource chemistry

Direct small team of medicinal chemists in the synthesis of analogues

Contribute to early discovery programs in pipeline

Improve on solubility/permeability of molecules

Look at data and interpret SARs

Serve as primary point of contact with CRO

Development of several assays: cytotoxicity, in-vitro aggregation assays, protein aggregation (ex-vivo tissue) Speak with company computational biologists on regular basis

Design chemistry analogues

Troubleshooting

Sthree US is acting as an Employment Agency in relation to this vacancy.