Associate Director, Medicinal Chemistry

Location: South San Francisco, California Salary: competitive
Sector: R&D Type: Permanent


Ph.D. in Chemistry, Medicinal Chemistry, or related field

3 years minimum experience, 5+ years ideal

Experience working with CROs

Strong theoretical foundation in chemistry

Worked from late-stage discovery to early development

Experience working with non-classical drug targets (protein-protein interaction)

Troubleshooting experience

Understand possibility of molecules based on composition

Manage outsourced chemistry


Manage outsource chemistry

Direct small team of medicinal chemists in the synthesis of analogues

Contribute to early discovery programs in pipeline

Improve on solubility/permeability of molecules

Look at data and interpret SARs

Serve as primary point of contact with CRO

Development of several assays: cytotoxicity, in-vitro aggregation assays, protein aggregation (ex-vivo tissue) Speak with company computational biologists on regular basis

Design chemistry analogues


Sthree US is acting as an Employment Agency in relation to this vacancy.