Associate Director, Medicinal Chemist

Title: Associate Director of Medicinal Chemistry

Location: South San Francisco

Salary: Competitive based on experience

Must Have's:

-Ph.D in chemistry or related

-3-5 years of Medicinal Chemistry Experience (Protein-Protein interactions, SAR Relationships, PK, Novel Chemistry)

-Previous Management Experience (direct reports and CROs)

-Experience working with cross-functional groups (i.e. biologists, analytical chemists, PK)

Responsibility:

-Designing chemical analogs and scouting routes to access analogs

-Manage lead optimization of a series of allosteric small molecule ligands

-Direct a small team of medicinal chemists in the synthesis of analogues

~70% performing desk work including: chemical design at computer, chemical docking (w/computational biologists), and working with CROs (weekly reports and troubleshooting)

~30% in the lab working with: analytical chemists, PK biologists, and other cross functional teams

-working daily with the Associate director of R&D on the assays to characterize compounds, look at data, and interpret structure to advance compounds

-contribute to early discovery programs in the company pipeline

-coordinate additional work in-house and outsourced for solubility and PK

-Interface with IP team to write patents

Sthree US is acting as an Employment Agency in relation to this vacancy.